The Museum of Contemporary Art Kampa is located on the island of Kampa in the historical building of the Owl Mills. The first memory of the Owl Mills dates back to the 15th century, the building survived several fires and wars, and is rightfully considered the national cultural heritage of the country.

For some time, the Owl Mills were in decline, but in 2000-2001, with the help of local authorities, the complex was reconstructed. The museum was opened in 2003 on the initiative of patron Meda Mladek, who donated most of the exhibits for it.

The Kampa Museum has three permanent exhibitions: Central European contemporary art, an exhibition of works by František Kupka and an exhibition of sculptures by Otto Gutfreund. The museum also regularly hosts short-term exhibitions of contemporary art by artists such as Yoko Ono and František Kupka.